 |
|
|
 |
Doudna Research Group Publications
Download all Doudna Research Group publications
.tgz - 81MB |
.zip - 81MB
Search PubMed for
Doudna
Research Group publications
2005-2009
Fukunaga R., Doudna JA (2009)
dsRNA with 5' overhangs contributes to endogenous and antiviral RNA silencing pathways in plants.
EMBO J. [Epub ahead of print]
Jinek M., Doudna, J.A. (2009)
A three-dimensional view of the molecular machinery of RNA interference.
Nature 457, 405-12.
Coyle S.M., Doudna, J.A. (2008)
Direct link between RACK1 function and localization at the ribosome in vivo.
Mol Cell Biol. [Epub ahead of print]
Mehle, A. and Doudna, J.A. (2008)
An inhibitory activity in human cells restricts the function of an avian-like influenza virus polymerase.
Cell Host Microbe 4, 111-122.
(1.3MB .pdf)
Zhou, M., Sandercock, A.M., Fraser, C.S., Ridlova, G., Stephens, E., Schenauer, M.R., Yokoi-Fong, T., Barsky, D., Leary, J.A., Hershey, J.W., Doudna, J.A. and Robinson, C.V. (2008)
Special Feature: Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3.
PNAS Epub ahead of print.
(972KB .pdf)
Puglisi, J.D. and Doudna, J.A. (2008)
Nucleic acids and their protein partners.
Curr. Opin. Struct. Biol. 18, 279-281.
(98KB .pdf)
Ma, E., MacRae, I.J., Kirsch, J.F., and Doudna, J.A. (2008)
Autoinhibition of human dicer by its internal helicase domain.
J. Mol. Biol. 380, 237-243.
(360KB .pdf)
MacRae, I.J., Ma, E., Zhou, M., Robinson, C.V. and Doudna, J.A. (2008)
In vitro reconstitution of the human RISC-loading complex.
PNAS 105, 512-517.
(1.8MB .pdf)
Fraser, C.S. and Doudna, J.A. (2007)
Quantitative studies of ribosome conformational dynamics.
Q Rev Biophys. 40, 163-189.
(308KB .pdf)
MacRae, I.J., Zhou, K. and Doudna, J.A. (2007)
Structural determinants of RNA recognition and cleavage by Dicer.
Nat. Struct. Mol. Biol. 14, 934-940.
(488KB .pdf)
Gilbert, W.V., Zhou, K., Butler, T.K. and Doudna, J.A. (2007)
Cap-independent translation is required for starvation-induced differentiation in yeast.
Science 317, 1224-1227.
(380KB .pdf)
Fraser, C.S., Berry, K.E., Hershey, J.W. and Doudna, J.A. (2007)
eIF3j is located in the decoding center of the human 40S ribosomal subunit.
Mol. Cell. 26, 811-819.
(1.4MB .pdf)
MacRae, I.J. and Doudna, J.A. (2007)
An unusual case of pseudo-merohedral twinning in orthorhombic crystals of Dicer.
Acta Cryst. D 63(Part 9), 993-999.
(1.4MB .pdf)
Doudna, J.A. and Sarnow, P. (2007)
Translation initiation by viral internal ribosome entry sites.
In Translational Control in Biology and Medicine (Mathews, M.B., Sonenberg, N. and Hershey, J.W.B., Eds.),
Cold Spring Harbor Monograph 48, pp. 129-153.
(2.8MB .pdf)
Doudna, J.A. (2007)
The right chemistry: an updated nucleic acids textbook.
ACS Chem Biol. 2, 211-212.
(152KB .pdf)
Kiessling, L.L., Doudna, J.A., Johnsson, K., Mapp, A.K., Marletta, M.A., Seeberger, P.H., Williamson, J.R. and Wedde S.G. (2007)
A higher degree of difficulty.
ACS Chem Biol. 2, 197-199.
(292KB .pdf)
Ke, A., Ding, F., Batchelor, J.D. and Doudna, J.A. (2007)
Structural roles of monovalent cations in the HDV ribozyme.
Structure. 15, 281-287.
(1.1MB .pdf)
Damoc, E., Fraser, C.S., Zhou, M., Videler, H., Mayeur, G.L., Hershey, J.W., Doudna, J.A., Robinson, C.V. and Leary, J.A. (2007)
Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry.
Mol. Cell. Proteomics. 6, 1135-1146.
(604KB .pdf)
MacRae, I.J. and Doudna, J.A. (2007)
Ribonuclease revisited: structural insights into ribonuclease III family enzymes.
Curr. Opin. Struct. Biol. 17, 1-8.
(1.7MB .pdf)
Fraser, C.S. and Doudna, J.A. (2007)
Structural and mechanistic insights into hepatitis C viral translation initiation.
Nat. Rev. Microbiol. 5, 29-38.
(680KB .pdf)
MacRae, I.J., Li, F., Zhou, K., Cande, W.Z. and Doudna, J.A. (2006)
Structure of dicer and mechanistic implications for RNAi.
Cold Spring Harb. Symp. Quant. Biol. 71, 73-80.
(6.8MB .pdf)
Siu, F.Y., Spanggord, R.J. and Doudna, J.A. (2006)
SRP RNA provides the physiologically essential GTPase activation function in cotranslational protein targeting.
RNA 13, 240-250.
(1.1MB .pdf)
Green, R. and Doudna, J.A. (2006)
RNAs regulate biology.
ACS Chem. Biol. 1, 335-338.
(304KB .pdf)
Wu, S., Ke, A. and Doudna, J.A. (2006)
A fast and efficient procedure to produce scFvs specific for large macromolecular complexes.
J. Immunol. Methods 318, 95-101.
(876KB .pdf)
Chmiel, N.H., Rio, D.C. and Doudna, J.A. (2006)
Distinct contributions of KH domains to substrate binding affinity of Drosophila P-element somatic inhibitor protein.
RNA 12, 283-291.
(764KB .pdf)
MacRae, I.J., Zhou, K., Li, F., Repic, A., Brooks, A.N., Cande, W.Z., Adams, P.D. and Doudna, J.A. (2006)
Structural basis for double-stranded RNA processing by Dicer.
Science 311, 195-198.
(288KB .pdf)
(Figure)
(Structure)
Karbstein, K. and Doudna, J.A. (2006)
GTP-dependent formation of a ribonucleoprotein subcomplex required for ribosome biogenesis.
J. Mol. Biol. 356, 432-443.
(300KB .pdf)
Doudna, J.A. (2005)
Chemical biology at the crossroads of molecular structure and mechanism.
Nat. Chem. Biol. 1, 300-303.
(428KB .pdf)
Siridechadilok, B., Fraser, C.S., Hall, R.J., Doudna, J.A. and Nogales, E. (2005)
Structural roles for human translation factor eIF3 in initiation of protein synthesis.
Science 310, 1513-1515.
(216KB .pdf)
(Supplemental material: 712KB .pdf)
(Figure and QuickTime Movies)
(Structures)
Karbstein, K., Jonas, S. and Doudna, J.A. (2005)
An essential GTPase promotes assembly of preribosomal RNA processing complexes.
Mol. Cell 20, 633-643.
(504KB .pdf)
Spanggord, R.J., Siu, F., Ke, A. and Doudna, J.A. (2005)
RNA-mediated interaction between the peptide-binding and GTPase domains of the signal recognition particle.
Nat. Struct. Mol. Biol. 12, 1116-1122.
(484KB .pdf)
(Figures)
Chen, L., Lullo, D.J., Ma, E., Celniker, S.E., Rio, D.C. and Doudna, J.A. (2005)
Identification and analysis of U5 snRNA variants in Drosophila.
RNA 11, 1473-7.
(268KB .pdf)
MacRae, I. J. and Doudna, J.A. (2005)
Ro's Role in RNA Reconnaissance.
Cell 121, 495-496.
(80KB .pdf)
Yu, Y., Ji, H., Doudna, J.A. and Leary, J.A. (2005)
Mass spectrometric analysis of the human 40S ribosomal subunit: Native and HCV IRES-bound complexes.
Protein Sci. 14, 1438-1446.
(192KB .pdf)
Doudna, J.A. and Lorsch, J.R. (2005)
Ribozyme catalysis: not different, just worse.
Nat. Struct. Mol. Biol. 12, 395-402.
(580KB .pdf)
Aggarwal, A.K. and Doudna, J.A. (2005)
Editorial Overview: Protein-nucleic acid interactions: unlocking mysteries old and new.
Curr. Opin. Struct. Biol. 15, 65-67.
(72KB .pdf)
..: Return to top :..
2000-2004
Ji, H., Fraser, C.S., Yu, Y., Leary, J. and Doudna, J.A. (2004)
Coordinated assembly of human translation initiation complexes by the hepatitis C virus internal ribosome entry site RNA.
PNAS 101, 16990-16995.
(508KB .pdf)
(Figure)
Ke, A. and Doudna, J.A. (2004)
Crystallization of RNA and RNA-protein complexes.
Methods 34, 408-414.
(376KB .pdf)
Rambo, R.P. and Doudna, J.A. (2004)
Assembly of an active group II intron-maturase complex by protein dimerization.
Biochemistry 43, 6486-6497.
(396KB .pdf)
Luptak, A. and Doudna, J.A. (2004)
Distinct sites of phosphorothioate substitution interfere with folding and splicing of the Anabaena group I intron.
Nucleic Acid Res. 32, 2272-2280.
(312KB .pdf)
Sagar, M.B., Lucast, L. and Doudna, J.A. (2004)
Conserved but nonessential interaction of SRP RNA with translation factor EF-G.
RNA 10, 772-778.
(136KB .pdf)
Ke, A., Zhou, K., Ding, F., Cate, J.H.D. and Doudna, J.A. (2004)
A conformational switch controls hepatitis delta virus ribozyme catalysis.
Nature 429, 201-205.
(348KB .pdf)
(Figures and QuickTime Movies)
(Structures)
Karbstein, K. and Doudna, J.A. (2004)
RNA: Primed for Packing?
Chemistry and Biology 11, 149-151.
(148KB .pdf)
Doudna, J.A. and Batey, R.T. (2003)
Structural insights into the signal recognition particle.
Ann. Rev. Biochem. 73, 539-557.
(680KB .pdf)
Aggarwal, A.K. and Doudna, J.A. (2003)
Editorial Overview: Protein-nucleic acid interactions.
Curr. Opin. Struct. Biol. 13, 3-5.
(56KB .pdf)
Fraser, C.S., Lee, J.Y., Mayeur, G.L., Bushell, M., Doudna, J.A. and Hershey, J.W. (2003)
The j-subunit of human translation initiation factor eIF3 is required for the stable binding of eIF3 and its subcomplexes to 40 S ribosomal subunits in vitro.
J. Biol. Chem. 279, 8946-8956.
(532KB .pdf)
Doudna, J.A. and Cech, T.R. (2002)
The chemical repertoire of natural ribozymes.
Nature 418, 222-228.
(244KB .pdf)
Doudna, J.A. and Rath, V.L. (2002)
Structure and function of the eukaryotic ribosome: The next frontier.
Cell 109, 153-156.
(120KB .pdf)
Kieft, J.S., Zhou, K., Grech, A., Jubin. R. and Doudna, J.A. (2002)
Crystal structure of an RNA tertiary domain essential to HCV IRES-mediated translation initiation.
Nat. Struct. Biol. 9, 370-374.
(1.3MB .pdf)
(Structure)
Batey, R.T. and Doudna, J.A. (2002)
Structural and energetic analysis of metal ions essential to SRP signal recognition domain assembly.
Biochemistry 41, 11703-11710.
(536KB .pdf)
Battle, D.J. and Doudna, J.A. (2002)
Specificity of RNA-RNA helix recognition.
PNAS 99, 11676-11681.
(576KB .pdf)
Erratum: PNAS 99, 15831-15835.
(624KB .pdf)
(Structure)
Zhang, L. and Doudna, J.A. (2002)
Structural insights into group II intron catalysis and branch-site selection.
Science 295, 2084-2088.
(352KB .pdf)
(Structure)
Murray, J. and Doudna, J.A. (2001)
Creative catalysis: pieces of the RNA world jigsaw.
Trends Biochem. Sci. 26, 699-701.
(44KB .pdf)
Kieft, J.S., Grech, A., Adams, P. and Doudna, J.A. (2001)
Mechanisms of internal ribosome entry in translation initiation.
Cold Spring Harb. Symp. Quant. Biol. 66, 277-283.
(264KB .pdf)
Doudna, J.A. and Richmond, T.J. (2001)
Editorial Overview: Protein-nucleic acid interactions.
Curr. Opin. Struct. Biol. 11, 11-13.
(40KB .pdf)
Luptak, A., Ferré-D'Amaré, A.R., Zhou, K., Zilm, K.W. and Doudna, J.A. (2001)
Direct pKa measurement of the active-site cytosine in a genomic hepatitis delta virus ribozyme.
J. Am. Chem. Soc. 123, 8447-8452.
(88KB .pdf)
Doherty, E.A. and Doudna, J.A. (2001)
Ribozyme Structures and Mechanisms.
Ann. Rev. Biophys. Biomol. Struct. 30, 457-475.
(316KB .pdf)
Doherty, E.A., Batey, R.T., Masquida, B. and Doudna, J.A. (2001)
A universal mode of helix packing in RNA.
Nat. Struct. Biol. 8, 339-343.
(1.6MB .pdf)
Spahn, C.M.T., Kieft, J.S., Grassucci, R.A., Penczek, P., Zhou, K., Doudna, J.A. and Frank, J. (2001)
Hepatitis C virus IRES RNA-induced changes in the conformation of the 40S ribosomal subunit.
Science 291, 1959-1962.
(348KB .pdf)
(Figure and Movie)
Batey, R.T., Sagar, M.B. and Doudna, J.A. (2001)
Structural and energetic analysis of RNA recognition by a universally conserved protein from the signal recognition particle.
J. Mol. Biol. 307, 229-246.
(840KB .pdf)
(Figure)
(Structure)
Lucast, L.J., Batey, R.T. and Doudna, J.A. (2001)
Large-scale purification of a stable form of recombinant tobacco etch virus protease.
Biotechniques 30, 544-554.
(108KB .pdf)
Kieft, J.S., Zhou, K., Jubin, R. and Doudna, J.A. (2001)
Mechanism of ribosome recruitment by hepatitis C IRES RNA.
RNA 7, 194-206.
(3.6MB .pdf)
Battle, D.J. and Doudna, J.A. (2001)
The stem-loop binding protein forms a highly stable and specific complex with the 3' stem-loop of histone mRNAs.
RNA 7, 123-132.
(452KB .pdf)
Erratum: RNA 7, 642-643.
Ferré-D'Amaré, A.R. and Doudna, J.A. (2000)
Methods to crystallize RNA.
In Current Protocols in Nucleic Acid Chemistry (Beaucage, S.L., Bergstrom, D.E., Glick, G.D. and Jones, R.A., Eds.), pgs. 7.6.1-7.6.13, John Wiley & Sons, New York.
(204KB .pdf)
Hanna, R. and Doudna, J.A. (2000)
Metal ions in ribozyme folding and catalysis.
Curr. Opin. Chem. Biol. 4, 166-170.
(228KB .pdf)
Doudna, J.A. (2000)
Structural genomics of RNA.
Nature Struct. Biol. 7, Suppl., 954-956.
(148KB .pdf)
Doherty, E.A. and Doudna, J.A. (2000)
Ribozyme Structures and Mechanisms.
Ann. Rev. Biochem. 69, 597-615.
(2.0MB .pdf)
Cate, J.H. and Doudna, J.A. (2000)
Solving large RNA structures by x-ray crystallography.
Meth. Enzymol. 317, 169-180.
(1.9MB .pdf)
Jeruzalmi D., Kuriyan J., Doudna J. (2000)
Paul Sigler (1934-2000).
Trends Biochem Sci. 25, 221-2.
(188KB .pdf)
Jubin, R., Vantuno, N.E., Kieft, J.S., Murray, M.G., Doudna, J.A., Lau, J.Y. and Baroudy, B.M. (2000)
Hepatitis C virus internal ribosome entry site (IRES) stem loop IIId contains a phylogenetically conserved GGG triplet essential for translation and IRES folding.
J. Virol 22, 10430-10437.
(248KB .pdf)
Hanna, R.L., Gryaznov, S.M. and Doudna, J.A. (2000)
A phosphoramidate substrate analog is a competitive inhibitor of the Tetrahymena group I ribozyme.
Chemistry and Biology 7, 845-854.
(524KB .pdf)
Engelhardt, M.A., Doherty, E.A., Knitt, D.S., Doudna, J.A., Herschlag, D. (2000)
The P5abc peripheral element facilitates preorganization of the Tetrahymena group I ribozyme for catalysis.
Biochemistry 39, 2639-2651.
(296KB .pdf)
Batey, R.T., Rambo, R.P., Lucast, L., Rha, B. and Doudna, J.A. (2000)
Crystal structure of the ribonucleoprotein core of the signal recognition particle.
Science 287, 1232-1239.
(2.0MB .pdf)
(Figure)
(Structure)
Comment: Science 287, 1212-1213.
Ferré-D'Amaré, A.R. and Doudna, J.A. (2000)
Crystallization and structure determination of a hepatitis delta virus ribozyme: Use of the RNA-binding protein U1A as a crystallization module.
J. Mol. Biol. 295, 541-556.
(900KB .pdf)
..: Return to top :..
1995-1999
Doudna, J.A. (1999)
Cashing in on Crystals.
Curr. Biol. 9 (19), R731-R734.
(76KB .pdf)
Batey, R.T, Rambo, R. and Doudna, J.A. (1999)
Tertiary motifs in RNA structure and folding.
Angewandte Chemie 38, 2327-2343.
(468KB .pdf)
Ferré-D'Amaré, A.R. and Doudna, J.A. (1999)
RNA folds: Insights from recent crystal structures.
Ann. Rev. Biophys. Biomolec. Struct. 28, 57-73.
(648KB .pdf)
Kieft, J.S., Zhou, K., Jubin, R., Murray, M.G., Johnson, Y.N.L. and Doudna, J.A. (1999)
The hepatitis C virus internal ribosome entry site adopts an ion-dependent tertiary fold.
J. Mol. Biol. 292, 513-529.
(676KB .pdf)
Wadkins, T.S., Perrotta, A.T., Ferré-D'Amaré, A.R., Doudna, J.A. and Been, M.D. (1999)
A nested double pseudoknot is required for self-cleavage activity of both the genomic and antigenomic hepatitis delta virus ribozymes.
RNA 5, 720-727.
(676KB .pdf)
Doherty, E.A., Herschlag, D. and Doudna, J.A. (1999)
Assembly of an exceptionally stable RNA tertiary interface in a group I ribozyme.
Biochem. 38, 2982-2990.
(176KB .pdf)
Doudna, J.A. and Cate, J.H. (1999)
RNA structures determined by X-ray crystallography.
In Comprehensive Natural Products Chemistry (Söll, D., Nishimura, S. and Moore, P.B., Eds.), Vol. 6, pp. 49-61.
(1.5MB .pdf)
Doudna, J.A. (1998)
Ribozymes: the hammerhead swings into action.
Curr. Biol. 8 (14), R495-R497.
(136KB .pdf)
Batey, R.T. and Doudna, J.A. (1998)
The parallel universe of RNA folding.
Nat. Struct. Biol. 5, 337-340.
(1.1MB .pdf)
Ferré-D'Amaré, A.R., Zhou, K. and Doudna J.A. (1998)
Crystal structure of a hepatitis delta virus ribozyme.
Nature 395, 567-574.
(684KB .pdf)
(Figures and QuickTime Movies)
(Structures)
Basu, S., Rambo, R., Strauss-Soukup, J., Cate, J.H., Ferré-D'Amaré, A.R., Strobel, S.A. and Doudna, J.A. (1998)
A specific monovalent metal ion integral to the AA platform of the RNA tetraloop receptor.
Nature Struc. Biol. 5(11), 986-992.
(1.0MB .pdf)
Ferré-D'Amaré, A.R., Zhou, K. and Doudna, J.A. (1998)
A general module for RNA crystallization.
J. Mol. Biol. 279, 621-631.
(420KB .pdf)
Doudna, J.A. (1997)
RNA structure. A molecular contortionist.
Nature 338, 830-831.
(268KB .pdf)
Doudna, J.A. (1997)
Book Review - Catalytic RNA, edited by Fritz Eckstein and David M.J. Lilley. 1996. Nucleic Acids and Molecular Biology, Vol. 10. Heidelberg: Springer-Verlag. 418 pp.
RNA 3, 1083-1084.
(360KB .pdf)
Doudna, J.A. and Doherty, E.A. (1997)
Emerging themes in RNA folding.
Folding and Design 2, R65-70.
(948KB .pdf)
Doudna, J.A. and Cate, J.H. (1997)
RNA structure: crystal clear?
Curr. Opin. Struct. Biol. 7, 310-316.
(652KB .pdf)
Strobel, S.A. and Doudna, J.A. (1997)
RNA seeing double: close-packing of helices in RNA tertiary structure.
Trends in Biochem. Sci. 22, 262-266.
(1.0MB .pdf)
Cate, J.H. and Doudna, J.A. (1997)
A Sparse Matrix Approach to Crystallizing Ribozymes and RNA Motifs.
In Ribozyme Protocols, Methods in Molecular Biology Series (P. Turner, Ed.), Vol. 74, pp. 379-386, Humana Press:Totowa, NJ.
(732KB .pdf)
Ferré-D'Amaré, A.R. and Doudna, J.A. (1997)
Establishing Suitability of RNA Preparations for Crystallization. Determination of Polydispersity.
In Ribozyme Protocols, Methods in Molecular Biology Series (P. Turner, Ed.), Vol. 74, pp. 371-378, Humana Press:Totowa, NJ.
(672KB .pdf)
Doudna, J.A. (1997)
Preparation of Homogeneous Ribozyme RNA for Crystallization.
In Ribozyme Protocols, Methods in Molecular Biology Series (P. Turner, Ed.), Vol. 74, pp. 365-370, Humana Press:Totowa, NJ.
(612KB .pdf)
Cate, J.H., Hanna, R.H. and Doudna, J.A. (1997)
A magnesium ion core at the heart of a ribozyme domain.
Nat. Struct. Biol. 4, 553-558.
(968KB .pdf)
Comment: Nat. Struct. Biol. 4, 509-512.
Erratum: Nat. Struct. Biol. 4, 840.
Doherty, E.A. and Doudna, J.A. (1997)
The P4-P6 domain directs higher order folding of the Tetrahymena ribozyme core.
Biochemistry 36, 3159-69.
(392KB .pdf)
Cate, J.H. and Doudna, J.A. (1996)
Metal-binding sites in the major groove of a large ribozyme domain.
Structure 4, 1221-29.
(1.2MB .pdf)
Cate, J.H., Gooding, A., Podell, E., Zhou, K., Golden, B., Szewczak, A., Kundrot, C., Cech, T.R. and Doudna, J.A. (1996)
RNA tertiary structure mediation by adenosine platforms.
Science 273, 1696-99.
(156KB .pdf)
Cate, J.H., Gooding, A., Podell, E., Zhou, K., Golden, B., Kundrot, C., Cech, T.R. and Doudna, J.A. (1996)
Crystal structure of a group I ribozyme domain: Principles of RNA packing.
Science 273, 1678-85.
(360KB .pdf)
(Figure)
(Structure)
Jones, J.T., Barnes, C.L., Lietzke, S.E., Weichenrieder, O., Doudna, J.A. and Kundrot, C.E. (1996)
Preliminary x-ray diffraction studies of an RNA pseudoknot that inhibits HIV-1 reverse transcriptase.
Acta Cryst. D 52(Part 5), 1018-1020.
(840KB .pdf)
Ferré-D'Amaré, A.R. and Doudna, J.A. (1996)
Use of cis- and trans-ribozymes to remove 5' and 3' heterogeneities from milligrams of in vitro transcribed RNA.
Nucleic Acids Res. 24, 977-78.
(40KB .pdf)
Doudna, J.A. (1995)
Hammerhead ribozyme structure: U-turn for RNA structural biology.
Structure 3, 747-750.
(472KB .pdf)
Doudna, J.A. and Cech, T.R. (1995)
Self-assembly of a group I intron active site from its component tertiary structural domains.
RNA 1, 36-45.
(5.7MB .pdf)
Doudna, J.A., Cech, T.R. and Sullenger, B.A. (1995)
Selection of an RNA molecule that mimics a major autoantigenic epitope of human insulin receptor.
PNAS 92, 2355-59.
(1.1MB .pdf)
..: Return to top :..
1987-1994
Doudna, J.A. (1994)
Hammering out the shape of a ribozyme.
Structure 2, 1271-72.
(292KB .pdf)
Cech, T.R., Bevilacqua, P.C., Doudna, J.A., McConnell, T.S., Strobel, S.A. and Weinstein, L.A. (1993)
Mechanism and Structure of a Catalytic RNA Molecule.
In Proceedings of The Robert A. Welch Foundation 37th Conference on Chemical Research: 40 Years of the DNA Double Helix, Houston, Texas, pp. 91-110.
(2.0MB .pdf)
Doudna, J.A., Grosshans, C., Gooding, A. and Kundrot, C.E. (1993)
Crystallization of ribozymes and small RNA folding motifs by a sparse matrix method.
PNAS 90, 7829-33.
(1.0MB .pdf)
Doudna, J.A., Usman, N. and Szostak, J.W. (1993)
RNA-catalyzed primer extension by tri-nucleotides: a model for the RNA-catalyzed replication of RNA.
Biochemistry 32, 2111-15.
(1.6MB .pdf)
Musier-Forsyth, K., Usman, N., Scaringe, S., Doudna, J., Green, R. and Schimmel, P. (1991)
Specificity for aminoacylation of an RNA helix: an unpaired, exocyclic amino group in the minor groove.
Science 253, 784-86.
(748KB .pdf)
Doudna, J.A., Couture, S. and Szostak, J.W. (1991)
A multisubunit ribozyme that is a catalyst of and template for complementary strand RNA synthesis.
Science 251, 1605-1608.
(1.3MB .pdf)
Bartel, D.P., Doudna, J.A., Usman, N. and Szostak, J.W. (1991)
Template-directed primer extension catalyzed by the Tetrahymena ribozyme.
Mol. Cell. Biol. 11, 3390-94.
(1.2MB .pdf)
Doudna, J.A., Szostak, J.W., Rich, A. and Usman, N. (1990)
Chemical synthesis of oligo-ribonucleotides containing 2-aminopurine: Substrates for the investigation of ribozyme function.
J. Org. Chem. 55, 5547-49.
(1.3MB .pdf)
Couture, S., Ellington, A.D., Gerber, A.S., Cherry, J.M., Doudna, J.A., Green, R., Hanna, M., Pace, U., Rajagopal, J. and Szostak, J.W. (1990)
Mutational analysis of conserved nucleotides in a self-splicing group I intron.
J. Mol. Biol. 215, 345-358.
(2.1MB .pdf)
Doudna, J.A. and Szostak, J.W. (1989)
Mini ribozymes, small derivatives of the sunY intron, are catalytically active.
Mol. Cell. Biol. 9, 5480-83.
(796KB .pdf)
Doudna, J.A. and Szostak, J.W. (1989)
RNA catalyzed synthesis of complementary strand RNA.
Nature 339, 519-22.
(444KB .pdf)
Rajagopal, J., Doudna, J.A. and Szostak, J.W. (1989)
Stereochemical course of catalysis by the Tetrahymena ribozyme.
Science 244, 692-94.
(920KB .pdf)
Doudna, J.A., Cormack, B.P. and Szostak, J.W. (1989)
RNA structure, not sequence, determines the 5' splice-site specificity of a group I intron.
PNAS 86, 7402-7406.
(1.0MB .pdf)
Doudna, J.A., Cherry, J.M., Gerber, A.S. and Szostak, J.W. (1987)
Genetic dissection of an RNA enzyme.
Cold Spring Harb. Symp. Quant. Biol. 52, 173-180.
(1.2MB .pdf)
..: Return to top :..
|
|
|
 |
|
