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Kaihong Zhou

Selected Publications

Macrae, I.J., Zhou, K., and Doudna, J.A. (2007) Structural determinants of RNA recognition and cleavage by Dicer. Nat. Struct. Mol. Biol. 2007 Sep 16 [Epub ahead of print]. (508KB .pdf)

Gilbert, W.V., Zhou, K., Butler, T.K. and Doudna, J.A. (2007) Cap-independent translation is required for starvation-induced differentiation in yeast. Science 317, 1224-1227. (380KB .pdf)

Macrae, I.J., Li, F., Zhou, K., Cande, W.Z. and Doudna, J.A. (2006) Structure of dicer and mechanistic implications for RNAi. Cold Spring Harbor Symp. Quant. Biol. 71, 73-80. (6.8MB .pdf)

MacRae, I.J., Zhou, K., Li, F., Repic, A., Brooks, A.N., Cande, W.Z., Adams, P.D., and Doudna, J.A. (2006) Structural basis for double-stranded RNA processing by Dicer. Science 311, 195-198. (288KB .pdf) (Figure) (Structure)

Ke, A., Zhou, K., Ding, F., Cate, J.H.D. and Doudna, J.A. (2004) A conformational switch controls hepatitis delta virus ribozyme catalysis. Nature, 429, 201-205. (348KB .pdf) (Figures and QuickTime Movies) (Structures)

Kieft, J.S., Zhou, K., Grech, A., Jubin. R. and Doudna, J.A. (2002) Crystal structure of an RNA tertiary domain essential to HCV IRES-mediated translation initiation. Nat. Struct. Biol. 9, 370-374. (1356KB .pdf) (Structure)

Luptak, A., Ferré-D'Amaré, A.R., Zhou, K., Zilm, K.W. and Doudna, J.A. (2001) Direct pKa measurement of the active-site cytosine in a genomic hepatitis delta virus ribozyme. J. Am. Chem. Soc. 123, 8447-8452. (88KB .pdf)

Spahn, C.M.T., Kieft, J.S., Grassucci, R.A., Penczek, P., Zhou, K., Doudna, J.A. and Frank, J. (2001) Hepatitis C virus IRES RNA-induced changes in the conformation of the 40S ribosomal subunit. Science 291, 1959-1962. (348KB .pdf) (Figure and Movie)

Kieft, J.S., Zhou, K., Jubin, R. and Doudna, J.A. (2001) Mechanism of ribosome recruitment by hepatitis C IRES RNA. RNA 7, 194-206. (3568KB .pdf)

Kieft, J.S., Zhou, K., Jubin, R., Murray, M.G., Johnson, Y.N.L. and Doudna, J.A. (1999) The hepatitis C virus internal ribosome entry site adopts an ion-dependent tertiary fold. J. Mol. Biol. 292, 513-529. (676KB .pdf)

Ferré-D'Amaré, A.R., Zhou, K. and Doudna J.A. (1998) Crystal structure of a hepatitis delta virus ribozyme. Nature 395, 567-574. (684KB .pdf) (Figures and QuickTime Movies) (Structures)

Ferré-D'Amaré, A.R., Zhou, K. and Doudna, J.A. (1998) A general module for RNA crystallization. J. Mol. Biol. 279, 621-631. (420KB .pdf)

Cate, J.H., Gooding, A., Podell, E., Zhou, K., Golden, B., Szewczak, A., Kundrot, C., Cech, T.R. and Doudna, J.A. (1996) RNA tertiary structure mediation by adenosine platforms. Science 273, 1696-99. (156KB .pdf)

Cate, J.H., Gooding, A., Podell, E., Zhou, K., Golden, B., Kundrot, C., Cech, T.R. and Doudna, J.A. (1996) Crystal structure of a group I ribozyme domain: Principles of RNA packing. Science 273, 1678-85. (360KB .pdf) (Figure) (Structure)

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